Pancreatic Cancer PDAC I. MEK/ERK PATHWAY IN PDAC (FOCUS ONLY IN PANCERATIC CANCER ) A. Targeted Therapy and Function Talk about the targeted therapy in general and special in the downstream signals MEK and ERK in pancreatic cancer B. Combined Therapy Talk about monotherapy vs combined therapy including a novel target specially in PDAC Feedback that may affect the monotherapy. In another word targeting one thing resulting in switching on another thing